Though they appear as human girls, they are beings different from humans — spirits. Possessing immense power, whenever they manifest from the neighboring world, they cause disasters known as “Spatial Tremors.” Because of this, they are even called humanity’s natural enemies. The means humanity can take against the threat of these spirits are either to exterminate them by force, or… “go on a date and make them fall in love!” Shido Itsuka possesses the ability to seal a spirit’s power by making them fall in love and sharing a kiss. Using this power, he has been able to save both humanity and the spirits themselves. However, a major upheaval is about to unfold around him. DEM Industries, one of the world’s largest corporations and a group seeking the power of the spirits, launches an all-out assault to take Shido’s life.